Urban innovation hubs are the new urban campuses, with innovation and entrepreneurship at their core. Diverse players in major European cities are initiating projects geared towards building districts in which inhabitants live, work and learn together – building communities that drive cities forward. Developing such projects requires well-developed visions and strong partnerships. Here we hear the stories of some at the forefront of this development. What will be the role of city governments, investment partnerships, industry and universities in shaping and managing these future urban districts?